A standalone version of IsoFinder for the computational prediction of isochores in genome sequences

Isochores are long genome segments relatively homogeneous in G+C. A heuristic algorithm based on entropic segmentation has been developed by our group, and a web server implementing all the required components is available. However, a researcher may want to perform batch processing of many sequences simultaneously in its local machine, instead of analyzing them on one by one basis through the web. To this end, standalone versions are required. We report here the implementation of two standalone programs, able to predict isochores at the sequence level: 1) a command-line version (IsoFinder) for Windows and Linux systems; and 2) a user-friendly version (IsoFinderWin) running under Windows.Comment: 7 pages, 3 figure

Regulation and Incentives in European Aviation

We study the effect of liberalization on costs and competition in the European airline industry. We construct and estimate a model that includes demand, capacity, and cost equations. The latter accounts for inefficiency and cost-reducing effort. We show that failure to account for the choice of effort would lead to biased estimates of efficiency and competition in the industry. We also find that the last European Union package of deregulatory measures has led to significant efficiency improvements and has fostered competition.Publicad

Environmental accounting for ecosystem conservation: Linking societal and ecosystem metabolisms

This paper proposes an approach to environmental accounting useful for studying the feasibility of socio-economic systems in relation to the external constraints posed by ecological compatibility. The approach is based on a multi-scale analysis of the metabolic pattern of ecosystems and societies and it provides an integrated characterization of the resulting interaction. The text starts with a theoretical part explaining (i) the implicit epistemological revolution implied by the notion of ecosystem metabolism and the fund-flow model developed by Georgescu-Roegen applied to environmental accounting, and (ii) the potentials of this approach to create indicators to assess ecological integrity and environmental impacts. This revolution also makes it possible to carry out a multi-scale integrated assessment of ecosystem and societal metabolisms at the territorial level. In the second part, two applications of this approach using an indicator of the negentropic cost show the possibility to characterize in quantitative and qualitative terms degrees of alteration (crop cultivation, tree plantations)for different biomes (tropical and boreal forests). Also, a case study for land use scenarios has been included. The proposed approach represents an integrated multi-scale tool for the analysis of nature conservation scenarios and strategies.Comment: 29 pages including 6 figure